Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery
Mitochondria are key targets for photothermal and photodynamic treatment for cancer but delivery of therapeutics to these organelles remains a challenge. In this study, authors develop a mitochondrial targeted liposomal delivery platform using a dendritic peptide moiety as a mitochondria targeting m...
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| Autores principales: | , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/b523e89cd2e14554af8523e7a2b39849 |
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| Sumario: | Mitochondria are key targets for photothermal and photodynamic treatment for cancer but delivery of therapeutics to these organelles remains a challenge. In this study, authors develop a mitochondrial targeted liposomal delivery platform using a dendritic peptide moiety as a mitochondria targeting moiety and demonstrate its targeting and antitumour efficacy in a mouse model of breast cancer. |
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