A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii

A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii

Aerobic ethanol production, a phenomenon referred as Crabtree effect, allows yeast to outcompete other microorganisms in sugar rich environments. Here, the authors show that overexpression of a Gal4-like transcription factor can transform Komagataella phaffii from Crabtree effect negative to positiv...

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Autores principales: Özge Ata, Corinna Rebnegger, Nadine E. Tatto, Minoska Valli, Teresa Mairinger, Stephan Hann, Matthias G. Steiger, Pınar Çalık, Diethard Mattanovich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b5356eee23814a6a86e92955ca493d85
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spelling oai:doaj.org-article:b5356eee23814a6a86e92955ca493d852021-12-02T15:34:47ZA single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii10.1038/s41467-018-07430-42041-1723https://doaj.org/article/b5356eee23814a6a86e92955ca493d852018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07430-4https://doaj.org/toc/2041-1723Aerobic ethanol production, a phenomenon referred as Crabtree effect, allows yeast to outcompete other microorganisms in sugar rich environments. Here, the authors show that overexpression of a Gal4-like transcription factor can transform Komagataella phaffii from Crabtree effect negative to positive.Özge AtaCorinna RebneggerNadine E. TattoMinoska ValliTeresa MairingerStephan HannMatthias G. SteigerPınar ÇalıkDiethard MattanovichNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Özge Ata
Corinna Rebnegger
Nadine E. Tatto
Minoska Valli
Teresa Mairinger
Stephan Hann
Matthias G. Steiger
Pınar Çalık
Diethard Mattanovich
A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
description Aerobic ethanol production, a phenomenon referred as Crabtree effect, allows yeast to outcompete other microorganisms in sugar rich environments. Here, the authors show that overexpression of a Gal4-like transcription factor can transform Komagataella phaffii from Crabtree effect negative to positive.
format article
author Özge Ata
Corinna Rebnegger
Nadine E. Tatto
Minoska Valli
Teresa Mairinger
Stephan Hann
Matthias G. Steiger
Pınar Çalık
Diethard Mattanovich
author_facet Özge Ata
Corinna Rebnegger
Nadine E. Tatto
Minoska Valli
Teresa Mairinger
Stephan Hann
Matthias G. Steiger
Pınar Çalık
Diethard Mattanovich
author_sort Özge Ata
title A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
title_short A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
title_full A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
title_fullStr A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
title_full_unstemmed A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
title_sort single gal4-like transcription factor activates the crabtree effect in komagataella phaffii
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/b5356eee23814a6a86e92955ca493d85
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