Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction

Viral infection and vaccination both induce lasting persistence of antigens for protective responses. Here the authors show that migratory dendritic cells, independent of the transcription factor BatF3 for their development, contribute to “archived antigen” exchange with lymphatic endothelial cells....

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Autores principales: Ross M. Kedl, Robin S. Lindsay, Jeffrey M. Finlon, Erin D. Lucas, Rachel S. Friedman, Beth A. Jirón Tamburini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b537a9bda5cb458bb791cdc68bf23ee5
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Sumario:Viral infection and vaccination both induce lasting persistence of antigens for protective responses. Here the authors show that migratory dendritic cells, independent of the transcription factor BatF3 for their development, contribute to “archived antigen” exchange with lymphatic endothelial cells.