Comparing the renoprotective effects of BM-MSCs versus BM-MSC-exosomes, when combined with an anti-fibrotic drug, in hypertensive mice
Fibrosis, a hallmark of chronic kidney disease (CKD), impairs the viability of human bone marrow derived-mesenchymal stromal cells (BM-MSCs) post-transplantation. To address this, we demonstrated that combining BM-MSCs with the anti-fibrotic drug, serelaxin (RLX), enhanced BM-MSC-induced renoprotect...
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Main Authors: | Yifang Li, Amlan Chakraborty, Brad R.S. Broughton, Dorota Ferens, Robert E. Widdop, Sharon D. Ricardo, Chrishan S. Samuel |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Subjects: | |
Online Access: | https://doaj.org/article/b54d14cd5a744650955a465e368c1bac |
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