Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis

Abstract It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced OA in conplastic mice in order to evaluate the functional consequences of m...

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Autores principales: Morena Scotece, Ignacio Rego-Pérez, Ana Victoria Lechuga-Vieco, Alberto Centeno Cortés, María Concepción Jiménez-Gómez, Purificación Filgueira-Fernández, Carlos Vaamonde-García, José Antonio Enríquez, Francisco J. Blanco
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b5574bd366dc4090abea5086ff794bf4
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