Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.

<h4>Objective</h4>The objective of the present study was to compare 24-hour glycemic levels between obese pregnant women with normal glucose tolerance and non-obese pregnant women.<h4>Methods</h4>In the present observational, longitudinal study, continuous glucose monitoring...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rosa Maria Rahmi, Priscila de Oliveira, Luciano Selistre, Paulo Cury Rezende, Gabriela Neuvald Pezzella, Pâmela Antoniazzi Dos Santos, Daiane de Oliveira Pereira Vergani, Sônia Regina Cabral Madi, José Mauro Madi
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b55ecf7cba3b49429bec5cfb7dce7576
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b55ecf7cba3b49429bec5cfb7dce7576
record_format	dspace
spelling	oai:doaj.org-article:b55ecf7cba3b49429bec5cfb7dce75762021-12-02T20:10:46ZContinuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.1932-620310.1371/journal.pone.0253047https://doaj.org/article/b55ecf7cba3b49429bec5cfb7dce75762021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253047https://doaj.org/toc/1932-6203<h4>Objective</h4>The objective of the present study was to compare 24-hour glycemic levels between obese pregnant women with normal glucose tolerance and non-obese pregnant women.<h4>Methods</h4>In the present observational, longitudinal study, continuous glucose monitoring was performed in obese pregnant women with normal oral glucose tolerance test with 75 g of glucose between the 24th and the 28th gestational weeks. The control group (CG) consisted of pregnant women with normal weight who were selected by matching the maternal age and parity with the same characteristics of the obese group (OG). Glucose measurements were obtained during 72 hours.<h4>Results</h4>Both the groups were balanced in terms of baseline characteristics (age: 33.5 [28.7-36.0] vs. 32.0 [26.0-34.5] years, p = 0.5 and length of pregnancy: 25.0 [24.0-25.0] vs. 25.5 [24.0-28.0] weeks, p = 0.6 in the CG and in the OG, respectively). Pre-breakfast glycemic levels were 77.77 ± 10.55 mg/dL in the CG and 82.02 ± 11.06 mg/dL in the OG (p<0.01). Glycemic levels at 2 hours after breakfast were 87.31 ± 13.10 mg/dL in the CG and 93.48 ± 18.74 mg/dL in the OG (p<0.001). Daytime blood glucose levels were 87.6 ± 15.4 vs. 93.1 ± 18.3 mg/dL (p<0.001) and nighttime blood glucose levels were 79.3 ± 15.8 vs. 84.7 ± 16.3 mg/dL (p<0.001) in the CG and in the OG, respectively. The 24-hour, daytime, and nighttime values of the area under the curve were higher in the OG when compared with the CG (85.1 ± 0.16 vs. 87.9 ± 0.12, 65.6 ± 0.14 vs. 67.5 ± 0.10, 19.5 ± 0.07 vs. 20.4 ± 0.05, respectively; p<0.001).<h4>Conclusion</h4>The results of the present study showed that obesity in pregnancy was associated with higher glycemic levels even in the presence of normal findings on glucose tolerance test.Rosa Maria RahmiPriscila de OliveiraLuciano SelistrePaulo Cury RezendeGabriela Neuvald PezzellaPâmela Antoniazzi Dos SantosDaiane de Oliveira Pereira VerganiSônia Regina Cabral MadiJosé Mauro MadiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253047 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Rosa Maria Rahmi Priscila de Oliveira Luciano Selistre Paulo Cury Rezende Gabriela Neuvald Pezzella Pâmela Antoniazzi Dos Santos Daiane de Oliveira Pereira Vergani Sônia Regina Cabral Madi José Mauro Madi Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.
description	<h4>Objective</h4>The objective of the present study was to compare 24-hour glycemic levels between obese pregnant women with normal glucose tolerance and non-obese pregnant women.<h4>Methods</h4>In the present observational, longitudinal study, continuous glucose monitoring was performed in obese pregnant women with normal oral glucose tolerance test with 75 g of glucose between the 24th and the 28th gestational weeks. The control group (CG) consisted of pregnant women with normal weight who were selected by matching the maternal age and parity with the same characteristics of the obese group (OG). Glucose measurements were obtained during 72 hours.<h4>Results</h4>Both the groups were balanced in terms of baseline characteristics (age: 33.5 [28.7-36.0] vs. 32.0 [26.0-34.5] years, p = 0.5 and length of pregnancy: 25.0 [24.0-25.0] vs. 25.5 [24.0-28.0] weeks, p = 0.6 in the CG and in the OG, respectively). Pre-breakfast glycemic levels were 77.77 ± 10.55 mg/dL in the CG and 82.02 ± 11.06 mg/dL in the OG (p<0.01). Glycemic levels at 2 hours after breakfast were 87.31 ± 13.10 mg/dL in the CG and 93.48 ± 18.74 mg/dL in the OG (p<0.001). Daytime blood glucose levels were 87.6 ± 15.4 vs. 93.1 ± 18.3 mg/dL (p<0.001) and nighttime blood glucose levels were 79.3 ± 15.8 vs. 84.7 ± 16.3 mg/dL (p<0.001) in the CG and in the OG, respectively. The 24-hour, daytime, and nighttime values of the area under the curve were higher in the OG when compared with the CG (85.1 ± 0.16 vs. 87.9 ± 0.12, 65.6 ± 0.14 vs. 67.5 ± 0.10, 19.5 ± 0.07 vs. 20.4 ± 0.05, respectively; p<0.001).<h4>Conclusion</h4>The results of the present study showed that obesity in pregnancy was associated with higher glycemic levels even in the presence of normal findings on glucose tolerance test.
format	article
author	Rosa Maria Rahmi Priscila de Oliveira Luciano Selistre Paulo Cury Rezende Gabriela Neuvald Pezzella Pâmela Antoniazzi Dos Santos Daiane de Oliveira Pereira Vergani Sônia Regina Cabral Madi José Mauro Madi
author_facet	Rosa Maria Rahmi Priscila de Oliveira Luciano Selistre Paulo Cury Rezende Gabriela Neuvald Pezzella Pâmela Antoniazzi Dos Santos Daiane de Oliveira Pereira Vergani Sônia Regina Cabral Madi José Mauro Madi
author_sort	Rosa Maria Rahmi
title	Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.
title_short	Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.
title_full	Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.
title_fullStr	Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.
title_full_unstemmed	Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.
title_sort	continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/b55ecf7cba3b49429bec5cfb7dce7576
work_keys_str_mv	AT rosamariarahmi continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT prisciladeoliveira continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT lucianoselistre continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT paulocuryrezende continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT gabrielaneuvaldpezzella continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT pamelaantoniazzidossantos continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT daianedeoliveirapereiravergani continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT soniareginacabralmadi continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest AT josemauromadi continuousglucosemonitoringinobesepregnantwomenwithnohyperglycemiaonglucosetolerancetest
_version_	1718374968724553728

Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.

Ejemplares similares