EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance

Ephrins are transmembrane proteins involved in cell-cell communication, and implicated in cancer cell growth and progression. Here, the authors show that EphrinB2 expression is reduced in glioma cells both by genetic and epigenetic alterations and under hypoxia, through a HIF1α-mediated direct regul...

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Main Authors: C. Depner, H. zum Buttel, N. Böğürcü, A. M. Cuesta, M. R. Aburto, S. Seidel, F. Finkelmeier, F. Foss, J. Hofmann, K. Kaulich, S. Barbus, M. Segarra, G. Reifenberger, B. K. Garvalov, T. Acker, A. Acker-Palmer
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/b5621b9d2c974229858dc255a24f288b
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