Extensive regression in pigmented skin lesions: a dangerous confounding feature

Spontaneous regression in melanomas is not an uncommon phenomenon, as it has been described in 10-35% of primary cutaneous lesions [1]. Regression does not appear to predict a more favorable course, since even fully regressed melanomas may progress into metastatic disease [2]. Several dermoscopic f...

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Autores principales:	Aimilios Lallas, Zoe Apalla, Elvira Moscarella, Iris Zalaudek, Thrasivoulos Tzellos, Ioanna Lefaki, Carlo Cota, Giuseppe Argenziano
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2012
Materias:	pigmented lesion regression melanoma lichen plants-like keratosis Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/b565141cc933438a9aa6c2bf5b57ee6e
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spelling	oai:doaj.org-article:b565141cc933438a9aa6c2bf5b57ee6e2021-11-17T08:33:10ZExtensive regression in pigmented skin lesions: a dangerous confounding feature10.5826/dpc.0202a082160-9381https://doaj.org/article/b565141cc933438a9aa6c2bf5b57ee6e2012-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1169https://doaj.org/toc/2160-9381 Spontaneous regression in melanomas is not an uncommon phenomenon, as it has been described in 10-35% of primary cutaneous lesions [1]. Regression does not appear to predict a more favorable course, since even fully regressed melanomas may progress into metastatic disease [2]. Several dermoscopic features have been correlated with the regression process, including white scar-like depigmented areas and gray-blue, pepper-like granules, which correspond to dermal scarring, pigment incontinence and presence of melanophages [3,4]. Regression may occur not only in melanomas, but also in melanocytic nevi, which similarly may exhibit white areas and gray-blue granules or areas under dermoscopy [5]. Overall, white areas have been proposed to be associated with the fibrosis type of regression and gray-blue areas to the melanosis type of regression of melanocytic tumors [3]. Lichen planus like keratosis (LPLK) is considered to represent a regressed solar lentigo or seborrheic keratosis. Dermoscopy of LPLK at the late stage of the regression process reveals a diffuse gray-blue granular pattern, similar to that observed in regressed melanocytic lesions [6]. In this context, when evaluating skin lesions that exhibit high degree of regression, interpretation of dermoscopic findings may be problematic, especially when no other dermoscopic clues can be recognized. Aimilios LallasZoe ApallaElvira MoscarellaIris ZalaudekThrasivoulos TzellosIoanna LefakiCarlo CotaGiuseppe ArgenzianoMattioli1885articlepigmented lesionregressionmelanomalichen plants-like keratosisDermatologyRL1-803ENDermatology Practical & Conceptual (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	pigmented lesion regression melanoma lichen plants-like keratosis Dermatology RL1-803
spellingShingle	pigmented lesion regression melanoma lichen plants-like keratosis Dermatology RL1-803 Aimilios Lallas Zoe Apalla Elvira Moscarella Iris Zalaudek Thrasivoulos Tzellos Ioanna Lefaki Carlo Cota Giuseppe Argenziano Extensive regression in pigmented skin lesions: a dangerous confounding feature
description	Spontaneous regression in melanomas is not an uncommon phenomenon, as it has been described in 10-35% of primary cutaneous lesions [1]. Regression does not appear to predict a more favorable course, since even fully regressed melanomas may progress into metastatic disease [2]. Several dermoscopic features have been correlated with the regression process, including white scar-like depigmented areas and gray-blue, pepper-like granules, which correspond to dermal scarring, pigment incontinence and presence of melanophages [3,4]. Regression may occur not only in melanomas, but also in melanocytic nevi, which similarly may exhibit white areas and gray-blue granules or areas under dermoscopy [5]. Overall, white areas have been proposed to be associated with the fibrosis type of regression and gray-blue areas to the melanosis type of regression of melanocytic tumors [3]. Lichen planus like keratosis (LPLK) is considered to represent a regressed solar lentigo or seborrheic keratosis. Dermoscopy of LPLK at the late stage of the regression process reveals a diffuse gray-blue granular pattern, similar to that observed in regressed melanocytic lesions [6]. In this context, when evaluating skin lesions that exhibit high degree of regression, interpretation of dermoscopic findings may be problematic, especially when no other dermoscopic clues can be recognized.
format	article
author	Aimilios Lallas Zoe Apalla Elvira Moscarella Iris Zalaudek Thrasivoulos Tzellos Ioanna Lefaki Carlo Cota Giuseppe Argenziano
author_facet	Aimilios Lallas Zoe Apalla Elvira Moscarella Iris Zalaudek Thrasivoulos Tzellos Ioanna Lefaki Carlo Cota Giuseppe Argenziano
author_sort	Aimilios Lallas
title	Extensive regression in pigmented skin lesions: a dangerous confounding feature
title_short	Extensive regression in pigmented skin lesions: a dangerous confounding feature
title_full	Extensive regression in pigmented skin lesions: a dangerous confounding feature
title_fullStr	Extensive regression in pigmented skin lesions: a dangerous confounding feature
title_full_unstemmed	Extensive regression in pigmented skin lesions: a dangerous confounding feature
title_sort	extensive regression in pigmented skin lesions: a dangerous confounding feature
publisher	Mattioli1885
publishDate	2012
url	https://doaj.org/article/b565141cc933438a9aa6c2bf5b57ee6e
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Extensive regression in pigmented skin lesions: a dangerous confounding feature

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