Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder

The significance of rare and de novo variants in bipolar disorder is not well understood. Here, the authors have analyzed whole exome/genome data from trios to identify deleterious de novo variants associated with bipolar disorder.

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Autores principales:	Masaki Nishioka, An-a Kazuno, Takumi Nakamura, Naomi Sakai, Takashi Hayama, Kumiko Fujii, Koji Matsuo, Atsuko Komori, Mizuho Ishiwata, Yoshinori Watanabe, Takashi Oka, Nana Matoba, Muneko Kataoka, Ahmed N. Alkanaq, Kohei Hamanaka, Takashi Tsuboi, Toru Sengoku, Kazuhiro Ogata, Nakao Iwata, Masashi Ikeda, Naomichi Matsumoto, Tadafumi Kato, Atsushi Takata
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b566dcdf10494a0cb75a52d15029cc4f
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spelling	oai:doaj.org-article:b566dcdf10494a0cb75a52d15029cc4f2021-12-02T17:39:48ZSystematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder10.1038/s41467-021-23453-w2041-1723https://doaj.org/article/b566dcdf10494a0cb75a52d15029cc4f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23453-whttps://doaj.org/toc/2041-1723The significance of rare and de novo variants in bipolar disorder is not well understood. Here, the authors have analyzed whole exome/genome data from trios to identify deleterious de novo variants associated with bipolar disorder.Masaki NishiokaAn-a KazunoTakumi NakamuraNaomi SakaiTakashi HayamaKumiko FujiiKoji MatsuoAtsuko KomoriMizuho IshiwataYoshinori WatanabeTakashi OkaNana MatobaMuneko KataokaAhmed N. AlkanaqKohei HamanakaTakashi TsuboiToru SengokuKazuhiro OgataNakao IwataMasashi IkedaNaomichi MatsumotoTadafumi KatoAtsushi TakataNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Masaki Nishioka An-a Kazuno Takumi Nakamura Naomi Sakai Takashi Hayama Kumiko Fujii Koji Matsuo Atsuko Komori Mizuho Ishiwata Yoshinori Watanabe Takashi Oka Nana Matoba Muneko Kataoka Ahmed N. Alkanaq Kohei Hamanaka Takashi Tsuboi Toru Sengoku Kazuhiro Ogata Nakao Iwata Masashi Ikeda Naomichi Matsumoto Tadafumi Kato Atsushi Takata Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
description	The significance of rare and de novo variants in bipolar disorder is not well understood. Here, the authors have analyzed whole exome/genome data from trios to identify deleterious de novo variants associated with bipolar disorder.
format	article
author	Masaki Nishioka An-a Kazuno Takumi Nakamura Naomi Sakai Takashi Hayama Kumiko Fujii Koji Matsuo Atsuko Komori Mizuho Ishiwata Yoshinori Watanabe Takashi Oka Nana Matoba Muneko Kataoka Ahmed N. Alkanaq Kohei Hamanaka Takashi Tsuboi Toru Sengoku Kazuhiro Ogata Nakao Iwata Masashi Ikeda Naomichi Matsumoto Tadafumi Kato Atsushi Takata
author_facet	Masaki Nishioka An-a Kazuno Takumi Nakamura Naomi Sakai Takashi Hayama Kumiko Fujii Koji Matsuo Atsuko Komori Mizuho Ishiwata Yoshinori Watanabe Takashi Oka Nana Matoba Muneko Kataoka Ahmed N. Alkanaq Kohei Hamanaka Takashi Tsuboi Toru Sengoku Kazuhiro Ogata Nakao Iwata Masashi Ikeda Naomichi Matsumoto Tadafumi Kato Atsushi Takata
author_sort	Masaki Nishioka
title	Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
title_short	Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
title_full	Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
title_fullStr	Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
title_full_unstemmed	Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
title_sort	systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b566dcdf10494a0cb75a52d15029cc4f
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Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder

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