NON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT

Paediatric non-alcoholic fatty liver disease is a chronic liver disease resulting from excessive fat accumulation in the liver. It is closely associated with obesity and some other risk factors. In the last few years, its prevalence in the developed world has been increasing rapidly alongside paedia...

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Autores principales: Ana Šinkovec, Milanka Živanović, Martin Thaler, Jernej Brecelj
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Lenguaje:SL
Publicado: The Society for Children with Metabolic Disorders 2021
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Acceso en línea:https://doaj.org/article/b567f8e473b0478293690e0040bd8d88
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spelling oai:doaj.org-article:b567f8e473b0478293690e0040bd8d882021-11-08T17:58:04ZNON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT1318-44232712-396010.38031/slovpediatr-2021-3-05enhttps://doaj.org/article/b567f8e473b0478293690e0040bd8d882021-10-01T00:00:00Z http://www.slovenskapediatrija.si/Portals/0/Clanki/2021/Slovpediatr-2021-3-05en.pdf https://doaj.org/toc/1318-4423https://doaj.org/toc/2712-3960Paediatric non-alcoholic fatty liver disease is a chronic liver disease resulting from excessive fat accumulation in the liver. It is closely associated with obesity and some other risk factors. In the last few years, its prevalence in the developed world has been increasing rapidly alongside paediatric obesity. It is generally asymptomatic and is accidentally dis-covered when diagnosing other diseases or during systematic examinations. The additional presence of inflammatory signs is characteristic of non-alcoholic steatohepatitis, which may progress to cirrhosis and end-stage liver disease. The initial diagnosis is based on non-invasive methods (blood tests, ultrasound), but in some cases, the definite diagnosis is based on liver biopsy. Other causes of liver disease and hepatic steatosis must be excluded. The frequency and methods of follow-up are dependent on the presence of risk factors and the severity of the liver changes. First-line treatment is based on lifestyle changes with weight reduction, minimizing risk factors and increasing physical activity. Medical treatment or nutritional supplements are currently not prescribed due to insufficient evidence. A practical approach to a child with fatty liver disease is illustrated by a case presentation.Ana ŠinkovecMilanka ŽivanovićMartin ThalerJernej BreceljThe Society for Children with Metabolic Disordersarticlechildnon-alcoholic steatohepatitisnon-alcoholic fatty liver diseaserecommendationsMedicineRPediatricsRJ1-570SLSlovenska pediatrija, Vol 28, Iss 3, Pp 154-158 (2021)
institution DOAJ
collection DOAJ
language SL
topic child
non-alcoholic steatohepatitis
non-alcoholic fatty liver disease
recommendations
Medicine
R
Pediatrics
RJ1-570
spellingShingle child
non-alcoholic steatohepatitis
non-alcoholic fatty liver disease
recommendations
Medicine
R
Pediatrics
RJ1-570
Ana Šinkovec
Milanka Živanović
Martin Thaler
Jernej Brecelj
NON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT
description Paediatric non-alcoholic fatty liver disease is a chronic liver disease resulting from excessive fat accumulation in the liver. It is closely associated with obesity and some other risk factors. In the last few years, its prevalence in the developed world has been increasing rapidly alongside paediatric obesity. It is generally asymptomatic and is accidentally dis-covered when diagnosing other diseases or during systematic examinations. The additional presence of inflammatory signs is characteristic of non-alcoholic steatohepatitis, which may progress to cirrhosis and end-stage liver disease. The initial diagnosis is based on non-invasive methods (blood tests, ultrasound), but in some cases, the definite diagnosis is based on liver biopsy. Other causes of liver disease and hepatic steatosis must be excluded. The frequency and methods of follow-up are dependent on the presence of risk factors and the severity of the liver changes. First-line treatment is based on lifestyle changes with weight reduction, minimizing risk factors and increasing physical activity. Medical treatment or nutritional supplements are currently not prescribed due to insufficient evidence. A practical approach to a child with fatty liver disease is illustrated by a case presentation.
format article
author Ana Šinkovec
Milanka Živanović
Martin Thaler
Jernej Brecelj
author_facet Ana Šinkovec
Milanka Živanović
Martin Thaler
Jernej Brecelj
author_sort Ana Šinkovec
title NON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT
title_short NON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT
title_full NON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT
title_fullStr NON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT
title_full_unstemmed NON-ALCOHOLIC STEATOHEPATITIS IN CHILDREN − A PRACTICAL APPROACH WITH CASE REPORT
title_sort non-alcoholic steatohepatitis in children − a practical approach with case report
publisher The Society for Children with Metabolic Disorders
publishDate 2021
url https://doaj.org/article/b567f8e473b0478293690e0040bd8d88
work_keys_str_mv AT anasinkovec nonalcoholicsteatohepatitisinchildrenapracticalapproachwithcasereport
AT milankazivanovic nonalcoholicsteatohepatitisinchildrenapracticalapproachwithcasereport
AT martinthaler nonalcoholicsteatohepatitisinchildrenapracticalapproachwithcasereport
AT jernejbrecelj nonalcoholicsteatohepatitisinchildrenapracticalapproachwithcasereport
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