Human intrahepatic CD69 + CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity

Abstract Tissue resident memory T cells (TRM) have been identified in various tissues, however human liver TRM to date remain unidentified. TRM can be recognized by CD69 and/or CD103 expression and may play a role in the pathology of chronic hepatitis B (CHB) and hepatitis C virus infection (CHC). L...

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Auteurs principaux: Femke Stelma, Annikki de Niet, Marjan J. Sinnige, Karel A. van Dort, Klaas P. J. M. van Gisbergen, Joanne Verheij, Ester M. M. van Leeuwen, Neeltje A. Kootstra, Hendrik W. Reesink
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/b56880598d574792ab00d0e87c2e8df7
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