Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication

Enterovirus 71 (EV71) infection causes a spectrum of symptoms including neurological disease. To improve our understanding of EV71-host interactions, Wu et al. here perform a genome-wide RNAi screen, which implicates cell cycle regulation and ER-associated degradation as important factors in EV71 re...

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Autores principales:	Kan Xing Wu, Patchara Phuektes, Pankaj Kumar, Germaine Yen Lin Goh, Dimitri Moreau, Vincent Tak Kwong Chow, Frederic Bard, Justin Jang Hann Chu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b570f2103dc44d409e3bad0d44e49be7
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spelling	oai:doaj.org-article:b570f2103dc44d409e3bad0d44e49be72021-12-02T14:38:55ZHuman genome-wide RNAi screen reveals host factors required for enterovirus 71 replication10.1038/ncomms131502041-1723https://doaj.org/article/b570f2103dc44d409e3bad0d44e49be72016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13150https://doaj.org/toc/2041-1723Enterovirus 71 (EV71) infection causes a spectrum of symptoms including neurological disease. To improve our understanding of EV71-host interactions, Wu et al. here perform a genome-wide RNAi screen, which implicates cell cycle regulation and ER-associated degradation as important factors in EV71 replication.Kan Xing WuPatchara PhuektesPankaj KumarGermaine Yen Lin GohDimitri MoreauVincent Tak Kwong ChowFrederic BardJustin Jang Hann ChuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kan Xing Wu Patchara Phuektes Pankaj Kumar Germaine Yen Lin Goh Dimitri Moreau Vincent Tak Kwong Chow Frederic Bard Justin Jang Hann Chu Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
description	Enterovirus 71 (EV71) infection causes a spectrum of symptoms including neurological disease. To improve our understanding of EV71-host interactions, Wu et al. here perform a genome-wide RNAi screen, which implicates cell cycle regulation and ER-associated degradation as important factors in EV71 replication.
format	article
author	Kan Xing Wu Patchara Phuektes Pankaj Kumar Germaine Yen Lin Goh Dimitri Moreau Vincent Tak Kwong Chow Frederic Bard Justin Jang Hann Chu
author_facet	Kan Xing Wu Patchara Phuektes Pankaj Kumar Germaine Yen Lin Goh Dimitri Moreau Vincent Tak Kwong Chow Frederic Bard Justin Jang Hann Chu
author_sort	Kan Xing Wu
title	Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
title_short	Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
title_full	Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
title_fullStr	Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
title_full_unstemmed	Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
title_sort	human genome-wide rnai screen reveals host factors required for enterovirus 71 replication
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b570f2103dc44d409e3bad0d44e49be7
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Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication

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