Precapillary sphincters maintain perfusion in the cerebral cortex

Precapillary sphincters are mural cells encircling an indentation of blood vessels where capillaries branch off from penetrating arterioles (PAs), but their existence and role in the brain is not fully understood. Here authors describe these structures at PAs in the cortex and show that they constri...

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Autores principales:	Søren Grubb, Changsi Cai, Bjørn O. Hald, Lila Khennouf, Reena Prity Murmu, Aske G. K. Jensen, Jonas Fordsmann, Stefan Zambach, Martin Lauritzen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b57da6fb5b81419aa3f6193951425a37
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spelling	oai:doaj.org-article:b57da6fb5b81419aa3f6193951425a372021-12-02T13:27:30ZPrecapillary sphincters maintain perfusion in the cerebral cortex10.1038/s41467-020-14330-z2041-1723https://doaj.org/article/b57da6fb5b81419aa3f6193951425a372020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14330-zhttps://doaj.org/toc/2041-1723Precapillary sphincters are mural cells encircling an indentation of blood vessels where capillaries branch off from penetrating arterioles (PAs), but their existence and role in the brain is not fully understood. Here authors describe these structures at PAs in the cortex and show that they constrict during cortical spreading depolarization in mice.Søren GrubbChangsi CaiBjørn O. HaldLila KhennoufReena Prity MurmuAske G. K. JensenJonas FordsmannStefan ZambachMartin LauritzenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Søren Grubb Changsi Cai Bjørn O. Hald Lila Khennouf Reena Prity Murmu Aske G. K. Jensen Jonas Fordsmann Stefan Zambach Martin Lauritzen Precapillary sphincters maintain perfusion in the cerebral cortex
description	Precapillary sphincters are mural cells encircling an indentation of blood vessels where capillaries branch off from penetrating arterioles (PAs), but their existence and role in the brain is not fully understood. Here authors describe these structures at PAs in the cortex and show that they constrict during cortical spreading depolarization in mice.
format	article
author	Søren Grubb Changsi Cai Bjørn O. Hald Lila Khennouf Reena Prity Murmu Aske G. K. Jensen Jonas Fordsmann Stefan Zambach Martin Lauritzen
author_facet	Søren Grubb Changsi Cai Bjørn O. Hald Lila Khennouf Reena Prity Murmu Aske G. K. Jensen Jonas Fordsmann Stefan Zambach Martin Lauritzen
author_sort	Søren Grubb
title	Precapillary sphincters maintain perfusion in the cerebral cortex
title_short	Precapillary sphincters maintain perfusion in the cerebral cortex
title_full	Precapillary sphincters maintain perfusion in the cerebral cortex
title_fullStr	Precapillary sphincters maintain perfusion in the cerebral cortex
title_full_unstemmed	Precapillary sphincters maintain perfusion in the cerebral cortex
title_sort	precapillary sphincters maintain perfusion in the cerebral cortex
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b57da6fb5b81419aa3f6193951425a37
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Precapillary sphincters maintain perfusion in the cerebral cortex

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