HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN

Abstract. HLA DRB1* gene associations with idiopathic fetal losses and infertility were studied in women. It was shown that idiopathic fetal losses are associated with HLA DRB1*04 specificity, whereas infertility correlated with HLA DRB1*04/07 genotype. The associations revealed may indicate to a sp...

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Auteurs principaux:	L. A. Gordeeva, A. V. Shabaldin, A. N. Glushkov, O. A. Glushkova, O. S. Makarchenko, T. A. Simonova, I. V. Vetrova, E. A. Sherina, N. K. Zhilinskaya, V. I. Minina
Format:	article
Langue:	RU
Publié:	SPb RAACI 2014
Sujets:	hla reproductive disorders autoimmunity Immunologic diseases. Allergy RC581-607
Accès en ligne:	https://doaj.org/article/b580dbfa1a7d40d5a239e24e35a43601
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spelling	oai:doaj.org-article:b580dbfa1a7d40d5a239e24e35a436012021-11-18T08:03:39ZHLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN1563-06252313-741X10.15789/1563-0625-2007-6-643-648https://doaj.org/article/b580dbfa1a7d40d5a239e24e35a436012014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/258https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. HLA DRB1* gene associations with idiopathic fetal losses and infertility were studied in women. It was shown that idiopathic fetal losses are associated with HLA DRB104 specificity, whereas infertility correlated with HLA DRB104/07 genotype. The associations revealed may indicate to a special role of autoimmune events in women during pregnancy. The authors suggest a hypothesis on existence of several immune modes of reproductive losses. HLA genotyping may be applied as a basic technique for their determination.L. A. GordeevaA. V. ShabaldinA. N. GlushkovO. A. GlushkovaO. S. MakarchenkoT. A. SimonovaI. V. VetrovaE. A. SherinaN. K. ZhilinskayaV. I. MininaSPb RAACIarticlehlareproductive disordersautoimmunityImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 6, Pp 643-648 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	hla reproductive disorders autoimmunity Immunologic diseases. Allergy RC581-607
spellingShingle	hla reproductive disorders autoimmunity Immunologic diseases. Allergy RC581-607 L. A. Gordeeva A. V. Shabaldin A. N. Glushkov O. A. Glushkova O. S. Makarchenko T. A. Simonova I. V. Vetrova E. A. Sherina N. K. Zhilinskaya V. I. Minina HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN
description	Abstract. HLA DRB1* gene associations with idiopathic fetal losses and infertility were studied in women. It was shown that idiopathic fetal losses are associated with HLA DRB104 specificity, whereas infertility correlated with HLA DRB104/07 genotype. The associations revealed may indicate to a special role of autoimmune events in women during pregnancy. The authors suggest a hypothesis on existence of several immune modes of reproductive losses. HLA genotyping may be applied as a basic technique for their determination.
format	article
author	L. A. Gordeeva A. V. Shabaldin A. N. Glushkov O. A. Glushkova O. S. Makarchenko T. A. Simonova I. V. Vetrova E. A. Sherina N. K. Zhilinskaya V. I. Minina
author_facet	L. A. Gordeeva A. V. Shabaldin A. N. Glushkov O. A. Glushkova O. S. Makarchenko T. A. Simonova I. V. Vetrova E. A. Sherina N. K. Zhilinskaya V. I. Minina
author_sort	L. A. Gordeeva
title	HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN
title_short	HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN
title_full	HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN
title_fullStr	HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN
title_full_unstemmed	HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN
title_sort	hla drb1* association with reproductive disorders in women
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/b580dbfa1a7d40d5a239e24e35a43601
work_keys_str_mv	AT lagordeeva hladrb1associationwithreproductivedisordersinwomen AT avshabaldin hladrb1associationwithreproductivedisordersinwomen AT anglushkov hladrb1associationwithreproductivedisordersinwomen AT oaglushkova hladrb1associationwithreproductivedisordersinwomen AT osmakarchenko hladrb1associationwithreproductivedisordersinwomen AT tasimonova hladrb1associationwithreproductivedisordersinwomen AT ivvetrova hladrb1associationwithreproductivedisordersinwomen AT easherina hladrb1associationwithreproductivedisordersinwomen AT nkzhilinskaya hladrb1associationwithreproductivedisordersinwomen AT viminina hladrb1associationwithreproductivedisordersinwomen
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HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN

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