Robust single-cell DNA methylome profiling with snmC-seq2

Single-cell DNA methylome profiling allows the study of epigenomic heterogeneity in tissues but has been impeded by library quality. Here the authors demonstrate snmC-seq2 which improves mapping, throughput and library complexity.

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Autores principales:	Chongyuan Luo, Angeline Rivkin, Jingtian Zhou, Justin P. Sandoval, Laurie Kurihara, Jacinta Lucero, Rosa Castanon, Joseph R. Nery, António Pinto-Duarte, Brian Bui, Conor Fitzpatrick, Carolyn O’Connor, Seth Ruga, Marc E. Van Eden, David A. Davis, Deborah C. Mash, M. Margarita Behrens, Joseph R. Ecker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b58554dbcada4f7c8aeb1384ced312c3
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spelling	oai:doaj.org-article:b58554dbcada4f7c8aeb1384ced312c32021-12-02T15:34:04ZRobust single-cell DNA methylome profiling with snmC-seq210.1038/s41467-018-06355-22041-1723https://doaj.org/article/b58554dbcada4f7c8aeb1384ced312c32018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06355-2https://doaj.org/toc/2041-1723Single-cell DNA methylome profiling allows the study of epigenomic heterogeneity in tissues but has been impeded by library quality. Here the authors demonstrate snmC-seq2 which improves mapping, throughput and library complexity.Chongyuan LuoAngeline RivkinJingtian ZhouJustin P. SandovalLaurie KuriharaJacinta LuceroRosa CastanonJoseph R. NeryAntónio Pinto-DuarteBrian BuiConor FitzpatrickCarolyn O’ConnorSeth RugaMarc E. Van EdenDavid A. DavisDeborah C. MashM. Margarita BehrensJoseph R. EckerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chongyuan Luo Angeline Rivkin Jingtian Zhou Justin P. Sandoval Laurie Kurihara Jacinta Lucero Rosa Castanon Joseph R. Nery António Pinto-Duarte Brian Bui Conor Fitzpatrick Carolyn O’Connor Seth Ruga Marc E. Van Eden David A. Davis Deborah C. Mash M. Margarita Behrens Joseph R. Ecker Robust single-cell DNA methylome profiling with snmC-seq2
description	Single-cell DNA methylome profiling allows the study of epigenomic heterogeneity in tissues but has been impeded by library quality. Here the authors demonstrate snmC-seq2 which improves mapping, throughput and library complexity.
format	article
author	Chongyuan Luo Angeline Rivkin Jingtian Zhou Justin P. Sandoval Laurie Kurihara Jacinta Lucero Rosa Castanon Joseph R. Nery António Pinto-Duarte Brian Bui Conor Fitzpatrick Carolyn O’Connor Seth Ruga Marc E. Van Eden David A. Davis Deborah C. Mash M. Margarita Behrens Joseph R. Ecker
author_facet	Chongyuan Luo Angeline Rivkin Jingtian Zhou Justin P. Sandoval Laurie Kurihara Jacinta Lucero Rosa Castanon Joseph R. Nery António Pinto-Duarte Brian Bui Conor Fitzpatrick Carolyn O’Connor Seth Ruga Marc E. Van Eden David A. Davis Deborah C. Mash M. Margarita Behrens Joseph R. Ecker
author_sort	Chongyuan Luo
title	Robust single-cell DNA methylome profiling with snmC-seq2
title_short	Robust single-cell DNA methylome profiling with snmC-seq2
title_full	Robust single-cell DNA methylome profiling with snmC-seq2
title_fullStr	Robust single-cell DNA methylome profiling with snmC-seq2
title_full_unstemmed	Robust single-cell DNA methylome profiling with snmC-seq2
title_sort	robust single-cell dna methylome profiling with snmc-seq2
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b58554dbcada4f7c8aeb1384ced312c3
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Robust single-cell DNA methylome profiling with snmC-seq2

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