An interdigit signalling centre instructs coordinate phalanx-joint formation governed by 5′Hoxd–Gli3 antagonism
The molecular mechanisms governing digit joint specification are poorly understood. Here, the authors identify the 5′Hoxd–Gli3 balance as a key regulator of the net interdigital Bmp signalling level in mouse, which in turn regulates phalanx and joint formation.
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| Autores principales: | , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/b589df54b71a442db003ba86c874cc67 |
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