A peculiar case of psychosis: anti-NMDAr encephalitis

Abstract Background Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy...

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Autores principales:	Lamia Kouba, Dalia Alhosain
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Anti-NMDA receptor encephalitis Herpes simplex virus Psychosis Pregnancy Case report Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/b58aadeee27648afab1f87fe93592249
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spelling	oai:doaj.org-article:b58aadeee27648afab1f87fe935922492021-11-08T10:44:36ZA peculiar case of psychosis: anti-NMDAr encephalitis10.1186/s12245-021-00389-y1865-13721865-1380https://doaj.org/article/b58aadeee27648afab1f87fe935922492021-11-01T00:00:00Zhttps://doi.org/10.1186/s12245-021-00389-yhttps://doaj.org/toc/1865-1372https://doaj.org/toc/1865-1380Abstract Background Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. Case presentation A 20-year-old woman at 18 weeks gestation presented with agitation and a 3-day history of hallucinations. She had a prior hospitalization for HSV encephalitis 6 weeks before. Her laboratory workup was unremarkable except for positive anti-NMDAr antibodies in the CSF. The patient was treated with high-dose corticosteroids and plasmapheresis, and she was discharged 2 weeks later fully recovered. Conclusions Anti-NMDAr encephalitis can be the culprit behind a new-onset of psychosis in pregnancy. Early diagnosis and treatment are crucial.Lamia KoubaDalia AlhosainBMCarticleAnti-NMDA receptor encephalitisHerpes simplex virusPsychosisPregnancyCase reportMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENInternational Journal of Emergency Medicine, Vol 14, Iss 1, Pp 1-3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Anti-NMDA receptor encephalitis Herpes simplex virus Psychosis Pregnancy Case report Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	Anti-NMDA receptor encephalitis Herpes simplex virus Psychosis Pregnancy Case report Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Lamia Kouba Dalia Alhosain A peculiar case of psychosis: anti-NMDAr encephalitis
description	Abstract Background Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. Case presentation A 20-year-old woman at 18 weeks gestation presented with agitation and a 3-day history of hallucinations. She had a prior hospitalization for HSV encephalitis 6 weeks before. Her laboratory workup was unremarkable except for positive anti-NMDAr antibodies in the CSF. The patient was treated with high-dose corticosteroids and plasmapheresis, and she was discharged 2 weeks later fully recovered. Conclusions Anti-NMDAr encephalitis can be the culprit behind a new-onset of psychosis in pregnancy. Early diagnosis and treatment are crucial.
format	article
author	Lamia Kouba Dalia Alhosain
author_facet	Lamia Kouba Dalia Alhosain
author_sort	Lamia Kouba
title	A peculiar case of psychosis: anti-NMDAr encephalitis
title_short	A peculiar case of psychosis: anti-NMDAr encephalitis
title_full	A peculiar case of psychosis: anti-NMDAr encephalitis
title_fullStr	A peculiar case of psychosis: anti-NMDAr encephalitis
title_full_unstemmed	A peculiar case of psychosis: anti-NMDAr encephalitis
title_sort	peculiar case of psychosis: anti-nmdar encephalitis
publisher	BMC
publishDate	2021
url	https://doaj.org/article/b58aadeee27648afab1f87fe93592249
work_keys_str_mv	AT lamiakouba apeculiarcaseofpsychosisantinmdarencephalitis AT daliaalhosain apeculiarcaseofpsychosisantinmdarencephalitis AT lamiakouba peculiarcaseofpsychosisantinmdarencephalitis AT daliaalhosain peculiarcaseofpsychosisantinmdarencephalitis
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A peculiar case of psychosis: anti-NMDAr encephalitis

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