Exploring the genetic correlation between obesity-related traits and regional brain volumes: Evidence from UK Biobank cohort

Exploring the genetic correlation between obesity-related traits and regional brain volumes: Evidence from UK Biobank cohort

Objective: To determine whether there is a correlation between obesity-related variants and regional brain volumes. Methods: Based on a mixed linear model (MLM), we analyzed the association between 1,498 obesity-related SNPs in the GWAS Catalog and 164 regional brain volumes from 29,420 participants...

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Bibliographic Details
Main Authors: Xingchen Pan, Miaoran Zhang, Aowen Tian, Lanlan Chen, Zewen Sun, Liying Wang, Peng Chen
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
Obesity
Brain image-derived phenotypes
MLM-based association analysis
Genetic correlation
Computer applications to medicine. Medical informatics
R858-859.7
Neurology. Diseases of the nervous system
RC346-429
Online Access:https://doaj.org/article/b58b4d6d2ddd4233979b6dd7965c2fb0
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https://doaj.org/article/b58b4d6d2ddd4233979b6dd7965c2fb0

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