Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

Zamprogno et al. report a lung-on-a-chip of the second generation that mimics an array of alveoli with in vivo-like dimensions, based on a thin, stretchable collagen-elastin membrane used to reproduce the air-blood barrier functions. The membrane is stable, can be cultured on both sides for weeks, i...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Pauline Zamprogno, Simon Wüthrich, Sven Achenbach, Giuditta Thoma, Janick D. Stucki, Nina Hobi, Nicole Schneider-Daum, Claus-Michael Lehr, Hanno Huwer, Thomas Geiser, Ralph A. Schmid, Olivier T. Guenat
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b58e7abc6fe5449390fc885d757f1445
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b58e7abc6fe5449390fc885d757f1445
record_format	dspace
spelling	oai:doaj.org-article:b58e7abc6fe5449390fc885d757f14452021-12-02T10:44:14ZSecond-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane10.1038/s42003-021-01695-02399-3642https://doaj.org/article/b58e7abc6fe5449390fc885d757f14452021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01695-0https://doaj.org/toc/2399-3642Zamprogno et al. report a lung-on-a-chip of the second generation that mimics an array of alveoli with in vivo-like dimensions, based on a thin, stretchable collagen-elastin membrane used to reproduce the air-blood barrier functions. The membrane is stable, can be cultured on both sides for weeks, is biodegradable and its elastic properties allow mimicking respiratory motions by mechanically stretching the cells.Pauline ZamprognoSimon WüthrichSven AchenbachGiuditta ThomaJanick D. StuckiNina HobiNicole Schneider-DaumClaus-Michael LehrHanno HuwerThomas GeiserRalph A. SchmidOlivier T. GuenatNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Pauline Zamprogno Simon Wüthrich Sven Achenbach Giuditta Thoma Janick D. Stucki Nina Hobi Nicole Schneider-Daum Claus-Michael Lehr Hanno Huwer Thomas Geiser Ralph A. Schmid Olivier T. Guenat Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
description	Zamprogno et al. report a lung-on-a-chip of the second generation that mimics an array of alveoli with in vivo-like dimensions, based on a thin, stretchable collagen-elastin membrane used to reproduce the air-blood barrier functions. The membrane is stable, can be cultured on both sides for weeks, is biodegradable and its elastic properties allow mimicking respiratory motions by mechanically stretching the cells.
format	article
author	Pauline Zamprogno Simon Wüthrich Sven Achenbach Giuditta Thoma Janick D. Stucki Nina Hobi Nicole Schneider-Daum Claus-Michael Lehr Hanno Huwer Thomas Geiser Ralph A. Schmid Olivier T. Guenat
author_facet	Pauline Zamprogno Simon Wüthrich Sven Achenbach Giuditta Thoma Janick D. Stucki Nina Hobi Nicole Schneider-Daum Claus-Michael Lehr Hanno Huwer Thomas Geiser Ralph A. Schmid Olivier T. Guenat
author_sort	Pauline Zamprogno
title	Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
title_short	Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
title_full	Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
title_fullStr	Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
title_full_unstemmed	Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
title_sort	second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b58e7abc6fe5449390fc885d757f1445
work_keys_str_mv	AT paulinezamprogno secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT simonwuthrich secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT svenachenbach secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT giudittathoma secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT janickdstucki secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT ninahobi secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT nicoleschneiderdaum secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT clausmichaellehr secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT hannohuwer secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT thomasgeiser secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT ralphaschmid secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane AT oliviertguenat secondgenerationlungonachipwithanarrayofstretchablealveolimadewithabiologicalmembrane
_version_	1718396785237426176

Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

Ejemplares similares