Concurrent proinflammatory and apoptotic activity of a Helicobacter pylori protein (HP986) points to its role in chronic persistence.

Helicobacter pylori induces cytokine mediated changes in gastroduodenal pathophysiology, wherein, the activated macrophages at the sub-mucosal space play a central role in mounting innate immune response against the antigens. The bacterium gains niche through persistent inflammation and local immune...

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Bibliographic Details
Main Authors: Ayesha Alvi, Suhail A Ansari, Nasreen Z Ehtesham, Mohammed Rizwan, Savita Devi, Leonardo A Sechi, Insaf A Qureshi, Seyed E Hasnain, Niyaz Ahmed
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
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Online Access:https://doaj.org/article/b5a8cb8db61b4e7caa9e23f68b4d116f
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