Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress
Abstract Stat3 is an oncogene, frequently associated with malignant transformation. A body of evidence implicates that phospho-Stat3Y705 contributes to its nucleic translocation, while phospho-Stat3S727 leads to the accumulation in mitochondria. Both are of importance for tumor cell proliferation. I...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2017
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| Accès en ligne: | https://doaj.org/article/b5a8de17946a46a69f5deaff5b835776 |
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