Regulatory control of DNA end resection by Sae2 phosphorylation

It has previously been established that DNA end resection in yeast and in humans is under CDK control. Here the authors explain how phosphorylation regulates the capacity of Sae2 — the yeast orthologue of human CtIP — to promote DNA end resection.

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Autores principales:	Elda Cannavo, Dominic Johnson, Sara N. Andres, Vera M. Kissling, Julia K. Reinert, Valerie Garcia, Dorothy A. Erie, Daniel Hess, Nicolas H. Thomä, Radoslav I. Enchev, Matthias Peter, R. Scott Williams, Matt J. Neale, Petr Cejka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b5b662ab16c04fe787474e35772256f4
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spelling	oai:doaj.org-article:b5b662ab16c04fe787474e35772256f42021-12-02T15:34:21ZRegulatory control of DNA end resection by Sae2 phosphorylation10.1038/s41467-018-06417-52041-1723https://doaj.org/article/b5b662ab16c04fe787474e35772256f42018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06417-5https://doaj.org/toc/2041-1723It has previously been established that DNA end resection in yeast and in humans is under CDK control. Here the authors explain how phosphorylation regulates the capacity of Sae2 — the yeast orthologue of human CtIP — to promote DNA end resection.Elda CannavoDominic JohnsonSara N. AndresVera M. KisslingJulia K. ReinertValerie GarciaDorothy A. ErieDaniel HessNicolas H. ThomäRadoslav I. EnchevMatthias PeterR. Scott WilliamsMatt J. NealePetr CejkaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elda Cannavo Dominic Johnson Sara N. Andres Vera M. Kissling Julia K. Reinert Valerie Garcia Dorothy A. Erie Daniel Hess Nicolas H. Thomä Radoslav I. Enchev Matthias Peter R. Scott Williams Matt J. Neale Petr Cejka Regulatory control of DNA end resection by Sae2 phosphorylation
description	It has previously been established that DNA end resection in yeast and in humans is under CDK control. Here the authors explain how phosphorylation regulates the capacity of Sae2 — the yeast orthologue of human CtIP — to promote DNA end resection.
format	article
author	Elda Cannavo Dominic Johnson Sara N. Andres Vera M. Kissling Julia K. Reinert Valerie Garcia Dorothy A. Erie Daniel Hess Nicolas H. Thomä Radoslav I. Enchev Matthias Peter R. Scott Williams Matt J. Neale Petr Cejka
author_facet	Elda Cannavo Dominic Johnson Sara N. Andres Vera M. Kissling Julia K. Reinert Valerie Garcia Dorothy A. Erie Daniel Hess Nicolas H. Thomä Radoslav I. Enchev Matthias Peter R. Scott Williams Matt J. Neale Petr Cejka
author_sort	Elda Cannavo
title	Regulatory control of DNA end resection by Sae2 phosphorylation
title_short	Regulatory control of DNA end resection by Sae2 phosphorylation
title_full	Regulatory control of DNA end resection by Sae2 phosphorylation
title_fullStr	Regulatory control of DNA end resection by Sae2 phosphorylation
title_full_unstemmed	Regulatory control of DNA end resection by Sae2 phosphorylation
title_sort	regulatory control of dna end resection by sae2 phosphorylation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b5b662ab16c04fe787474e35772256f4
work_keys_str_mv	AT eldacannavo regulatorycontrolofdnaendresectionbysae2phosphorylation AT dominicjohnson regulatorycontrolofdnaendresectionbysae2phosphorylation AT saranandres regulatorycontrolofdnaendresectionbysae2phosphorylation AT veramkissling regulatorycontrolofdnaendresectionbysae2phosphorylation AT juliakreinert regulatorycontrolofdnaendresectionbysae2phosphorylation AT valeriegarcia regulatorycontrolofdnaendresectionbysae2phosphorylation AT dorothyaerie regulatorycontrolofdnaendresectionbysae2phosphorylation AT danielhess regulatorycontrolofdnaendresectionbysae2phosphorylation AT nicolashthoma regulatorycontrolofdnaendresectionbysae2phosphorylation AT radoslavienchev regulatorycontrolofdnaendresectionbysae2phosphorylation AT matthiaspeter regulatorycontrolofdnaendresectionbysae2phosphorylation AT rscottwilliams regulatorycontrolofdnaendresectionbysae2phosphorylation AT mattjneale regulatorycontrolofdnaendresectionbysae2phosphorylation AT petrcejka regulatorycontrolofdnaendresectionbysae2phosphorylation
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Regulatory control of DNA end resection by Sae2 phosphorylation

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