Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets.

Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets.

Glioblastomas (GBMs) are highly aggressive, invasive brain tumors with bad prognosis and unmet medical need. These tumors are heterogeneous being constituted by a variety of cells in different states of differentiation. Among these, cells endowed with stem properties, tumor initiating/propagating pr...

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Autores principales: Marie Fève, Jean-Michel Saliou, Maria Zeniou, Sarah Lennon, Christine Carapito, Jihu Dong, Alain Van Dorsselaer, Marie-Pierre Junier, Hervé Chneiweiss, Sarah Cianférani, Jacques Haiech, Marie-Claude Kilhoffer
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b5c7500719c4454496e5a2cb4762db5a
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