Copper-Catalyzed Synthesis of Coumarins. A Mini-Review

Coumarin (2<i>H</i>-chromen-2-one) derivatives have important uses in medicinal and synthetic chemistry, for example, as fluorescent probes. These properties have prompted chemists to develop efficient synthetic methods to synthesize the coumarin core and/or to functionalize it. In this...

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Autores principales: Renato Dalpozzo, Raffaella Mancuso
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Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/b5cb307077c34059a4f9a38805b3cf4b
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spelling oai:doaj.org-article:b5cb307077c34059a4f9a38805b3cf4b2021-11-25T17:06:35ZCopper-Catalyzed Synthesis of Coumarins. A Mini-Review10.3390/catal111113822073-4344https://doaj.org/article/b5cb307077c34059a4f9a38805b3cf4b2021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4344/11/11/1382https://doaj.org/toc/2073-4344Coumarin (2<i>H</i>-chromen-2-one) derivatives have important uses in medicinal and synthetic chemistry, for example, as fluorescent probes. These properties have prompted chemists to develop efficient synthetic methods to synthesize the coumarin core and/or to functionalize it. In this context, many metal-catalyzed syntheses of coumarins have been introduced; among them, copper-catalyzed reactions appear to be very promising owing to the non-toxicity and cheapness of copper complexes. In this mini-review, the results in this field are summarized. We hope to stimulate other applications of these complexes in the preparation of coumarin derivatives.Renato DalpozzoRaffaella MancusoMDPI AGarticlecoumarincopper compoundsmetal catalysisChemical technologyTP1-1185ChemistryQD1-999ENCatalysts, Vol 11, Iss 1382, p 1382 (2021)
institution DOAJ
collection DOAJ
language EN
topic coumarin
copper compounds
metal catalysis
Chemical technology
TP1-1185
Chemistry
QD1-999
spellingShingle coumarin
copper compounds
metal catalysis
Chemical technology
TP1-1185
Chemistry
QD1-999
Renato Dalpozzo
Raffaella Mancuso
Copper-Catalyzed Synthesis of Coumarins. A Mini-Review
description Coumarin (2<i>H</i>-chromen-2-one) derivatives have important uses in medicinal and synthetic chemistry, for example, as fluorescent probes. These properties have prompted chemists to develop efficient synthetic methods to synthesize the coumarin core and/or to functionalize it. In this context, many metal-catalyzed syntheses of coumarins have been introduced; among them, copper-catalyzed reactions appear to be very promising owing to the non-toxicity and cheapness of copper complexes. In this mini-review, the results in this field are summarized. We hope to stimulate other applications of these complexes in the preparation of coumarin derivatives.
format article
author Renato Dalpozzo
Raffaella Mancuso
author_facet Renato Dalpozzo
Raffaella Mancuso
author_sort Renato Dalpozzo
title Copper-Catalyzed Synthesis of Coumarins. A Mini-Review
title_short Copper-Catalyzed Synthesis of Coumarins. A Mini-Review
title_full Copper-Catalyzed Synthesis of Coumarins. A Mini-Review
title_fullStr Copper-Catalyzed Synthesis of Coumarins. A Mini-Review
title_full_unstemmed Copper-Catalyzed Synthesis of Coumarins. A Mini-Review
title_sort copper-catalyzed synthesis of coumarins. a mini-review
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/b5cb307077c34059a4f9a38805b3cf4b
work_keys_str_mv AT renatodalpozzo coppercatalyzedsynthesisofcoumarinsaminireview
AT raffaellamancuso coppercatalyzedsynthesisofcoumarinsaminireview
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