Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis

The concentration of divalent cations is well-known to influence molecular processes such as enzymatic activity and RNA folding. Here the authors attempt to reproduce physiological conditions for RNA folding in vitro and establish an important contribution of chelated magnesium ions in enhancing RNA...

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Autores principales:	Ryota Yamagami, Jamie L. Bingaman, Erica A. Frankel, Philip C. Bevilacqua
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b5ced1074e554fa39a75d8b11e9e1a20
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spelling	oai:doaj.org-article:b5ced1074e554fa39a75d8b11e9e1a202021-12-02T14:40:44ZCellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis10.1038/s41467-018-04415-12041-1723https://doaj.org/article/b5ced1074e554fa39a75d8b11e9e1a202018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04415-1https://doaj.org/toc/2041-1723The concentration of divalent cations is well-known to influence molecular processes such as enzymatic activity and RNA folding. Here the authors attempt to reproduce physiological conditions for RNA folding in vitro and establish an important contribution of chelated magnesium ions in enhancing RNA function.Ryota YamagamiJamie L. BingamanErica A. FrankelPhilip C. BevilacquaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ryota Yamagami Jamie L. Bingaman Erica A. Frankel Philip C. Bevilacqua Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
description	The concentration of divalent cations is well-known to influence molecular processes such as enzymatic activity and RNA folding. Here the authors attempt to reproduce physiological conditions for RNA folding in vitro and establish an important contribution of chelated magnesium ions in enhancing RNA function.
format	article
author	Ryota Yamagami Jamie L. Bingaman Erica A. Frankel Philip C. Bevilacqua
author_facet	Ryota Yamagami Jamie L. Bingaman Erica A. Frankel Philip C. Bevilacqua
author_sort	Ryota Yamagami
title	Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
title_short	Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
title_full	Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
title_fullStr	Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
title_full_unstemmed	Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
title_sort	cellular conditions of weakly chelated magnesium ions strongly promote rna stability and catalysis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b5ced1074e554fa39a75d8b11e9e1a20
work_keys_str_mv	AT ryotayamagami cellularconditionsofweaklychelatedmagnesiumionsstronglypromoternastabilityandcatalysis AT jamielbingaman cellularconditionsofweaklychelatedmagnesiumionsstronglypromoternastabilityandcatalysis AT ericaafrankel cellularconditionsofweaklychelatedmagnesiumionsstronglypromoternastabilityandcatalysis AT philipcbevilacqua cellularconditionsofweaklychelatedmagnesiumionsstronglypromoternastabilityandcatalysis
_version_	1718390192840114176

Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis

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