Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis

The concentration of divalent cations is well-known to influence molecular processes such as enzymatic activity and RNA folding. Here the authors attempt to reproduce physiological conditions for RNA folding in vitro and establish an important contribution of chelated magnesium ions in enhancing RNA...

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Autores principales: Ryota Yamagami, Jamie L. Bingaman, Erica A. Frankel, Philip C. Bevilacqua
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b5ced1074e554fa39a75d8b11e9e1a20
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