Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes

Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes

Ultrasensitive methods for detection of biomarkers for infectious disease are needed for diagnosing, monitoring and targeting treatment. Here the authors develop a digital assay for inflammatory markers, bacterial DNA and antibotic-resistance genes and apply it to characterise asthma patients and pr...

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Main Authors: M. Fatih Abasıyanık, Krysta Wolfe, Hoang Van Phan, Jing Lin, Bharathi Laxman, Steven R. White, Philip A. Verhoef, Gökhan M. Mutlu, Bhakti Patel, Savaş Tay
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/b5d1efb0f6d045c4b3695d27b42dc37d
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Summary:Ultrasensitive methods for detection of biomarkers for infectious disease are needed for diagnosing, monitoring and targeting treatment. Here the authors develop a digital assay for inflammatory markers, bacterial DNA and antibotic-resistance genes and apply it to characterise asthma patients and predict mortality from septic shock.

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