Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves

It is unclear what role calcium signalling plays in the Drosophila wing disc. Here, the authors show that on mechanical stress, slow, long-range intercellular calcium waves are initiated in vivo and ex vivo, mediated by the inositol-3-phosphate receptor, the calcium pump SERCA and gap junction compo...

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Autores principales:	Simon Restrepo, Konrad Basler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b5d379d1c5404867bd70a347782c2a54
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spelling	oai:doaj.org-article:b5d379d1c5404867bd70a347782c2a542021-12-02T17:32:21ZDrosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves10.1038/ncomms124502041-1723https://doaj.org/article/b5d379d1c5404867bd70a347782c2a542016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12450https://doaj.org/toc/2041-1723It is unclear what role calcium signalling plays in the Drosophila wing disc. Here, the authors show that on mechanical stress, slow, long-range intercellular calcium waves are initiated in vivo and ex vivo, mediated by the inositol-3-phosphate receptor, the calcium pump SERCA and gap junction component Inx2.Simon RestrepoKonrad BaslerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Simon Restrepo Konrad Basler Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves
description	It is unclear what role calcium signalling plays in the Drosophila wing disc. Here, the authors show that on mechanical stress, slow, long-range intercellular calcium waves are initiated in vivo and ex vivo, mediated by the inositol-3-phosphate receptor, the calcium pump SERCA and gap junction component Inx2.
format	article
author	Simon Restrepo Konrad Basler
author_facet	Simon Restrepo Konrad Basler
author_sort	Simon Restrepo
title	Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves
title_short	Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves
title_full	Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves
title_fullStr	Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves
title_full_unstemmed	Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves
title_sort	drosophila wing imaginal discs respond to mechanical injury via slow insp3r-mediated intercellular calcium waves
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b5d379d1c5404867bd70a347782c2a54
work_keys_str_mv	AT simonrestrepo drosophilawingimaginaldiscsrespondtomechanicalinjuryviaslowinsp3rmediatedintercellularcalciumwaves AT konradbasler drosophilawingimaginaldiscsrespondtomechanicalinjuryviaslowinsp3rmediatedintercellularcalciumwaves
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Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves

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