The DnaK Chaperone Uses Different Mechanisms To Promote and Inhibit Replication of <italic toggle="yes">Vibrio cholerae</italic> Chromosome 2

ABSTRACT Replication of Vibrio cholerae chromosome 2 (Chr2) depends on molecular chaperone DnaK to facilitate binding of the initiator (RctB) to the replication origin. The binding occurs at two kinds of site, 12-mers and 39-mers, which promote and inhibit replication, respectively. Here we show tha...

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Autores principales: Jyoti K. Jha, Mi Li, Rodolfo Ghirlando, Lisa M. Miller Jenkins, Alexander Wlodawer, Dhruba Chattoraj
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/b5d96285835341098d25f2238b1b137f
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