NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants
Longevity is often associated with stress resistance, but whether they are causally linked is incompletely understood. Here we investigate chemosensory-defective Caenorhabditis elegans mutants that are long-lived and stress resistant. We find that mutants in the intraflagellar transport protein gene...
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Autores principales: | Gabriel A Guerrero, Maxime J Derisbourg, Felix AMC Mayr, Laura E Wester, Marco Giorda, J Eike Dinort, Matías D Hartman, Klara Schilling, María José Alonso-De Gennaro, Ryan J Lu, Bérénice A Benayoun, Martin S Denzel |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
eLife Sciences Publications Ltd
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/b5da5aa2ccee4aeda56385feab2e8031 |
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