Interferon Gamma-Inducible Protein 16 of Peripheral Blood Mononuclear Cells May Sense Hepatitis B Virus Infection and Regulate the Antiviral Immunity

Interferon Gamma-Inducible Protein 16 of Peripheral Blood Mononuclear Cells May Sense Hepatitis B Virus Infection and Regulate the Antiviral Immunity

Interferon gamma-inducible protein 16 (IFI16) is a DNA sensor protein, which triggers interferon-beta (IFN-β) production. However, the role of IFI16 in the innate immunity against hepatitis B virus (HBV) remains controversial. Peripheral blood mononuclear cells (PBMCs) and serum specimens were colle...

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Autores principales: Yu-Qing Lu, Jing Wu, Xiang-Ji Wu, Hui Ma, Yan-Xiu Ma, Rong Zhang, Meng-Nan Su, Nan Wu, Gong-Yin Chen, Hong-Song Chen, Xiao-Ben Pan
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
IFI16
HBV
PBMCs
innate immunity
interferon
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/b5ddf7169d884f87b61f8326c6530a4c
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