Bias in recent miRBase annotations potentially associated with RNA quality issues

Abstract Although microRNAs are supposed to be stable in-vivo, degradation processes potentially blur our knowledge on the small oligonucleotides. We set to quantify the effect of degradation on microRNAs in mouse to identify causes for distorted microRNAs patterns. In liver, we found 298, 99 and 8...

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Autores principales: Nicole Ludwig, Meike Becker, Timo Schumann, Timo Speer, Tobias Fehlmann, Andreas Keller, Eckart Meese
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b5e7ede394c24184ad346b62cb222cde
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