DeepRank: a deep learning framework for data mining 3D protein-protein interfaces

The authors present DeepRank, a deep learning framework for the data mining of large sets of 3D protein-protein interfaces (PPI). They use DeepRank to address two challenges in structural biology: distinguishing biological versus crystallographic PPIs in crystal structures, and secondly the ranking...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Nicolas Renaud, Cunliang Geng, Sonja Georgievska, Francesco Ambrosetti, Lars Ridder, Dario F. Marzella, Manon F. Réau, Alexandre M. J. J. Bonvin, Li C. Xue
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/b5e9d64b96e1438795a4aebfc8e1dd1c
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

id	oai:doaj.org-article:b5e9d64b96e1438795a4aebfc8e1dd1c
record_format	dspace
spelling	oai:doaj.org-article:b5e9d64b96e1438795a4aebfc8e1dd1c2021-12-05T12:22:28ZDeepRank: a deep learning framework for data mining 3D protein-protein interfaces10.1038/s41467-021-27396-02041-1723https://doaj.org/article/b5e9d64b96e1438795a4aebfc8e1dd1c2021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27396-0https://doaj.org/toc/2041-1723The authors present DeepRank, a deep learning framework for the data mining of large sets of 3D protein-protein interfaces (PPI). They use DeepRank to address two challenges in structural biology: distinguishing biological versus crystallographic PPIs in crystal structures, and secondly the ranking of docking models.Nicolas RenaudCunliang GengSonja GeorgievskaFrancesco AmbrosettiLars RidderDario F. MarzellaManon F. RéauAlexandre M. J. J. BonvinLi C. XueNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicolas Renaud Cunliang Geng Sonja Georgievska Francesco Ambrosetti Lars Ridder Dario F. Marzella Manon F. Réau Alexandre M. J. J. Bonvin Li C. Xue DeepRank: a deep learning framework for data mining 3D protein-protein interfaces
description	The authors present DeepRank, a deep learning framework for the data mining of large sets of 3D protein-protein interfaces (PPI). They use DeepRank to address two challenges in structural biology: distinguishing biological versus crystallographic PPIs in crystal structures, and secondly the ranking of docking models.
format	article
author	Nicolas Renaud Cunliang Geng Sonja Georgievska Francesco Ambrosetti Lars Ridder Dario F. Marzella Manon F. Réau Alexandre M. J. J. Bonvin Li C. Xue
author_facet	Nicolas Renaud Cunliang Geng Sonja Georgievska Francesco Ambrosetti Lars Ridder Dario F. Marzella Manon F. Réau Alexandre M. J. J. Bonvin Li C. Xue
author_sort	Nicolas Renaud
title	DeepRank: a deep learning framework for data mining 3D protein-protein interfaces
title_short	DeepRank: a deep learning framework for data mining 3D protein-protein interfaces
title_full	DeepRank: a deep learning framework for data mining 3D protein-protein interfaces
title_fullStr	DeepRank: a deep learning framework for data mining 3D protein-protein interfaces
title_full_unstemmed	DeepRank: a deep learning framework for data mining 3D protein-protein interfaces
title_sort	deeprank: a deep learning framework for data mining 3d protein-protein interfaces
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b5e9d64b96e1438795a4aebfc8e1dd1c
work_keys_str_mv	AT nicolasrenaud deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT cunlianggeng deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT sonjageorgievska deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT francescoambrosetti deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT larsridder deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT dariofmarzella deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT manonfreau deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT alexandremjjbonvin deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces AT licxue deeprankadeeplearningframeworkfordatamining3dproteinproteininterfaces
_version_	1718372035827073024

DeepRank: a deep learning framework for data mining 3D protein-protein interfaces

Documents similaires