Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids

Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids

Abstract Current treatment options against hepatitis B and D virus (HBV/HDV) infections have only limited curative effects. Identification of Na+/taurocholate co-transporting polypeptide (NTCP) as the high-affinity hepatic receptor for both viruses in 2012 enables target-based development of HBV/HDV...

Full description

Saved in:
Bibliographic Details
Main Authors: Michael Kirstgen, Kira Alessandra Alicia Theresa Lowjaga, Simon Franz Müller, Nora Goldmann, Felix Lehmann, Sami Alakurtti, Jari Yli-Kauhaluoma, Dieter Glebe, Joachim Geyer
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b5edf866c0b64b18948a6735dc0b00e5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items