Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids
Abstract Current treatment options against hepatitis B and D virus (HBV/HDV) infections have only limited curative effects. Identification of Na+/taurocholate co-transporting polypeptide (NTCP) as the high-affinity hepatic receptor for both viruses in 2012 enables target-based development of HBV/HDV...
Enregistré dans:
Auteurs principaux: | Michael Kirstgen, Kira Alessandra Alicia Theresa Lowjaga, Simon Franz Müller, Nora Goldmann, Felix Lehmann, Sami Alakurtti, Jari Yli-Kauhaluoma, Dieter Glebe, Joachim Geyer |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/b5edf866c0b64b18948a6735dc0b00e5 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design
par: Oxana Kazakova, et autres
Publié: (2021) -
Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12).
par: Teija Parkkari, et autres
Publié: (2014) -
Site-selective C-H hydroxylation of pentacyclic triterpenoids directed by transient chiral pyridine-imino groups
par: Tong Mu, et autres
Publié: (2020) -
Pentacyclic Triterpenoids, Phytosteroids and Fatty Acid Isolated from the Stem-bark of Cola lateritia K. Schum. (Sterculiaceae) of Cameroon origin; Evaluation of Their Antibacterial Activity
par: Michael H.K. Kamdem, et autres
Publié: (2022) -
PENTACYCLIC TRITERPENES FROM Cirsium pascuarense
par: PÉREZ GUTIÉRREZ,ROSA MARTHA
Publié: (2005)