Generation of biologically active multi-sialylated recombinant human EPOFc in plants.
Hyperglycosylated proteins are more stable, show increased serum half-life and less sensitivity to proteolysis compared to non-sialylated forms. This applies particularly to recombinant human erythropoietin (rhEPO). Recent progress in N-glycoengineering of non-mammalian expression hosts resulted in...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2013
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/b5f06cfea02040d2973c071052b72e7a |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|