Distributed hybrid-indexing of compressed pan-genomes for scalable and fast sequence alignment.
Computational pan-genomics utilizes information from multiple individual genomes in large-scale comparative analysis. Genetic variation between case-controls, ethnic groups, or species can be discovered thoroughly using pan-genomes of such subpopulations. Whole-genome sequencing (WGS) data volumes a...
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Main Authors: | Altti Ilari Maarala, Ossi Arasalo, Daniel Valenzuela, Veli Mäkinen, Keijo Heljanko |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Online Access: | https://doaj.org/article/b60be0dcea1c4be5aa5b1e912ef8c9de |
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