Management options in decompensated cirrhosis

Neeral L Shah,1 Yasmin Pourkazemi Banaei,2 Kristen L Hojnowski,2 Scott L Cornella3 1Division of Gastroenterology and Hepatology, 2School of Medicine, 3Department of Medicine, University of Virginia, Charlottesville, VA, USA Abstract: Chronic injury to the liver from a variety of different sources c...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shah NL, Banaei YP, Hojnowski KL, Cornella SL
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/b61635e3d1744e75bc281b87545e9b68
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b61635e3d1744e75bc281b87545e9b68
record_format	dspace
spelling	oai:doaj.org-article:b61635e3d1744e75bc281b87545e9b682021-12-02T02:09:00ZManagement options in decompensated cirrhosis1179-1535https://doaj.org/article/b61635e3d1744e75bc281b87545e9b682015-07-01T00:00:00Zhttp://www.dovepress.com/management-options-in-decompensated-cirrhosis-peer-reviewed-article-HMERhttps://doaj.org/toc/1179-1535Neeral L Shah,1 Yasmin Pourkazemi Banaei,2 Kristen L Hojnowski,2 Scott L Cornella3 1Division of Gastroenterology and Hepatology, 2School of Medicine, 3Department of Medicine, University of Virginia, Charlottesville, VA, USA Abstract: Chronic injury to the liver from a variety of different sources can result in irreversible scarring of the liver, known as cirrhosis. Cirrhosis is a major cause of morbidity and mortality in the USA, and according to the Centers for Disease Control and Prevention was responsible for 31,903 deaths in 2010 alone. It is thus of the utmost importance to appropriately manage these patients in the inpatient and outpatient setting to improve morbidity and mortality. In this review, we address four major areas of cirrhosis management: outpatient management of portal hypertension with decompensation, hepatic encephalopathy, hepatorenal syndrome, and bleeding/coagulation issues. Outpatient management covers recommendations for health care maintenance and screening. Hepatic encephalopathy encompasses a brief review of pathophysiology, treatment in the acute setting, and long-term prevention. Hepatorenal syndrome is discussed in regards to pathophysiology and treatment in the hospital setting. Finally, a discussion of the assessment of coagulation profiles in cirrhosis and recommendations for bleeding and thrombosis complications is included. These topics are not all encompassing with regard to this complicated population, but rather an overview of a few medical problems that are commonly encountered in their care. Keywords: portal hypertension, hepatic encephalopathy, hepatorenal, coagulationShah NLBanaei YPHojnowski KLCornella SLDove Medical PressarticleDiseases of the digestive system. GastroenterologyRC799-869ENHepatic Medicine: Evidence and Research, Vol 2015, Iss default, Pp 43-50 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	Diseases of the digestive system. Gastroenterology RC799-869 Shah NL Banaei YP Hojnowski KL Cornella SL Management options in decompensated cirrhosis
description	Neeral L Shah,1 Yasmin Pourkazemi Banaei,2 Kristen L Hojnowski,2 Scott L Cornella3 1Division of Gastroenterology and Hepatology, 2School of Medicine, 3Department of Medicine, University of Virginia, Charlottesville, VA, USA Abstract: Chronic injury to the liver from a variety of different sources can result in irreversible scarring of the liver, known as cirrhosis. Cirrhosis is a major cause of morbidity and mortality in the USA, and according to the Centers for Disease Control and Prevention was responsible for 31,903 deaths in 2010 alone. It is thus of the utmost importance to appropriately manage these patients in the inpatient and outpatient setting to improve morbidity and mortality. In this review, we address four major areas of cirrhosis management: outpatient management of portal hypertension with decompensation, hepatic encephalopathy, hepatorenal syndrome, and bleeding/coagulation issues. Outpatient management covers recommendations for health care maintenance and screening. Hepatic encephalopathy encompasses a brief review of pathophysiology, treatment in the acute setting, and long-term prevention. Hepatorenal syndrome is discussed in regards to pathophysiology and treatment in the hospital setting. Finally, a discussion of the assessment of coagulation profiles in cirrhosis and recommendations for bleeding and thrombosis complications is included. These topics are not all encompassing with regard to this complicated population, but rather an overview of a few medical problems that are commonly encountered in their care. Keywords: portal hypertension, hepatic encephalopathy, hepatorenal, coagulation
format	article
author	Shah NL Banaei YP Hojnowski KL Cornella SL
author_facet	Shah NL Banaei YP Hojnowski KL Cornella SL
author_sort	Shah NL
title	Management options in decompensated cirrhosis
title_short	Management options in decompensated cirrhosis
title_full	Management options in decompensated cirrhosis
title_fullStr	Management options in decompensated cirrhosis
title_full_unstemmed	Management options in decompensated cirrhosis
title_sort	management options in decompensated cirrhosis
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/b61635e3d1744e75bc281b87545e9b68
work_keys_str_mv	AT shahnl managementoptionsindecompensatedcirrhosis AT banaeiyp managementoptionsindecompensatedcirrhosis AT hojnowskikl managementoptionsindecompensatedcirrhosis AT cornellasl managementoptionsindecompensatedcirrhosis
_version_	1718402672407609344

Management options in decompensated cirrhosis

Ejemplares similares