Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system

The transplantation of tissue-specific progenitor cells may be an approach in organ regeneration. Here the authors show that the nephron progenitor population of a developing mouse kidney, when ablated, can be replaced by exogenously supplied rat nephron progenitors, generating interspecies nephrons...

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Autores principales:	S. Yamanaka, S. Tajiri, T. Fujimoto, K. Matsumoto, S. Fukunaga, B. S. Kim, H. J. Okano, T. Yokoo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b61fa958ba624c5393de0249d5c0bab0
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spelling	oai:doaj.org-article:b61fa958ba624c5393de0249d5c0bab02021-12-02T14:40:49ZGeneration of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system10.1038/s41467-017-01922-52041-1723https://doaj.org/article/b61fa958ba624c5393de0249d5c0bab02017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01922-5https://doaj.org/toc/2041-1723The transplantation of tissue-specific progenitor cells may be an approach in organ regeneration. Here the authors show that the nephron progenitor population of a developing mouse kidney, when ablated, can be replaced by exogenously supplied rat nephron progenitors, generating interspecies nephrons.S. YamanakaS. TajiriT. FujimotoK. MatsumotoS. FukunagaB. S. KimH. J. OkanoT. YokooNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q S. Yamanaka S. Tajiri T. Fujimoto K. Matsumoto S. Fukunaga B. S. Kim H. J. Okano T. Yokoo Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
description	The transplantation of tissue-specific progenitor cells may be an approach in organ regeneration. Here the authors show that the nephron progenitor population of a developing mouse kidney, when ablated, can be replaced by exogenously supplied rat nephron progenitors, generating interspecies nephrons.
format	article
author	S. Yamanaka S. Tajiri T. Fujimoto K. Matsumoto S. Fukunaga B. S. Kim H. J. Okano T. Yokoo
author_facet	S. Yamanaka S. Tajiri T. Fujimoto K. Matsumoto S. Fukunaga B. S. Kim H. J. Okano T. Yokoo
author_sort	S. Yamanaka
title	Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
title_short	Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
title_full	Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
title_fullStr	Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
title_full_unstemmed	Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
title_sort	generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b61fa958ba624c5393de0249d5c0bab0
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Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system

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