Temperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells

Abstract Dengue and Zika are two of the most important human viral pathogens worldwide. In both cases, the envelope glycoprotein E is the main target of the antibody response. Recently, new complex quaternary epitopes were identified which are the consequence of the arrangement of the antiparallel E...

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Auteurs principaux: J. L. Slon Campos, S. Marchese, J. Rana, M. Mossenta, M. Poggianella, M. Bestagno, O. R. Burrone
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/b62962fcee53410a94398caacdecb0aa
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