Activation and evasion of type I interferon responses by SARS-CoV-2

The pandemic of SARS-CoV-2 post a significant threat to public health. Here the authors show, by screening 23 viral proteins, that both structural and non-structural SARS-CoV-2 proteins are capable of modulating host innate immunity and type interferon responses, with this information serves to warr...

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Autores principales: Xiaobo Lei, Xiaojing Dong, Ruiyi Ma, Wenjing Wang, Xia Xiao, Zhongqin Tian, Conghui Wang, Ying Wang, Li Li, Lili Ren, Fei Guo, Zhendong Zhao, Zhuo Zhou, Zichun Xiang, Jianwei Wang
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b6304083e6354cbfa40555132af15397
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spelling oai:doaj.org-article:b6304083e6354cbfa40555132af153972021-12-02T16:24:53ZActivation and evasion of type I interferon responses by SARS-CoV-210.1038/s41467-020-17665-92041-1723https://doaj.org/article/b6304083e6354cbfa40555132af153972020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17665-9https://doaj.org/toc/2041-1723The pandemic of SARS-CoV-2 post a significant threat to public health. Here the authors show, by screening 23 viral proteins, that both structural and non-structural SARS-CoV-2 proteins are capable of modulating host innate immunity and type interferon responses, with this information serves to warrant further studies on SARS-CoV-2 pathogenesis.Xiaobo LeiXiaojing DongRuiyi MaWenjing WangXia XiaoZhongqin TianConghui WangYing WangLi LiLili RenFei GuoZhendong ZhaoZhuo ZhouZichun XiangJianwei WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiaobo Lei
Xiaojing Dong
Ruiyi Ma
Wenjing Wang
Xia Xiao
Zhongqin Tian
Conghui Wang
Ying Wang
Li Li
Lili Ren
Fei Guo
Zhendong Zhao
Zhuo Zhou
Zichun Xiang
Jianwei Wang
Activation and evasion of type I interferon responses by SARS-CoV-2
description The pandemic of SARS-CoV-2 post a significant threat to public health. Here the authors show, by screening 23 viral proteins, that both structural and non-structural SARS-CoV-2 proteins are capable of modulating host innate immunity and type interferon responses, with this information serves to warrant further studies on SARS-CoV-2 pathogenesis.
format article
author Xiaobo Lei
Xiaojing Dong
Ruiyi Ma
Wenjing Wang
Xia Xiao
Zhongqin Tian
Conghui Wang
Ying Wang
Li Li
Lili Ren
Fei Guo
Zhendong Zhao
Zhuo Zhou
Zichun Xiang
Jianwei Wang
author_facet Xiaobo Lei
Xiaojing Dong
Ruiyi Ma
Wenjing Wang
Xia Xiao
Zhongqin Tian
Conghui Wang
Ying Wang
Li Li
Lili Ren
Fei Guo
Zhendong Zhao
Zhuo Zhou
Zichun Xiang
Jianwei Wang
author_sort Xiaobo Lei
title Activation and evasion of type I interferon responses by SARS-CoV-2
title_short Activation and evasion of type I interferon responses by SARS-CoV-2
title_full Activation and evasion of type I interferon responses by SARS-CoV-2
title_fullStr Activation and evasion of type I interferon responses by SARS-CoV-2
title_full_unstemmed Activation and evasion of type I interferon responses by SARS-CoV-2
title_sort activation and evasion of type i interferon responses by sars-cov-2
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/b6304083e6354cbfa40555132af15397
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