Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia.
<h4>Background</h4>The small intestine plays a crucial role in the pathophysiology of sepsis and has been referred to as the "motor" of the systemic inflammatory response. One proposed mechanism is that toxic gut-derived lipid factors, transported in mesenteric lymph, induce sy...
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Main Authors: | Jessica A Dominguez, Yan Xie, W Michael Dunne, Benyam P Yoseph, Eileen M Burd, Craig M Coopersmith, Nicholas O Davidson |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/b633ef9ab9164c3fad865c10a6aed4bb |
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