IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development

Immune cells contribute to the aortic wall destruction during abdominal aortic aneurysm (AAA) development. Here, Peshkova et al. show that cytokine signaling through interleukin-27 receptor is required for Angiotensin II-induced myelopoiesis and mature myeloid cells production, thus contributing to...

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Autores principales:	Iuliia O. Peshkova, Turan Aghayev, Aliia R. Fatkhullina, Petr Makhov, Elizaveta K. Titerina, Satoru Eguchi, Yin Fei Tan, Andrew V. Kossenkov, Marina V. Khoreva, Lyudmila V. Gankovskaya, Stephen M. Sykes, Ekaterina K. Koltsova
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b6343cfed5b940ac92570f7ff3c8787a
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spelling	oai:doaj.org-article:b6343cfed5b940ac92570f7ff3c8787a2021-12-02T14:38:57ZIL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development10.1038/s41467-019-13017-42041-1723https://doaj.org/article/b6343cfed5b940ac92570f7ff3c8787a2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13017-4https://doaj.org/toc/2041-1723Immune cells contribute to the aortic wall destruction during abdominal aortic aneurysm (AAA) development. Here, Peshkova et al. show that cytokine signaling through interleukin-27 receptor is required for Angiotensin II-induced myelopoiesis and mature myeloid cells production, thus contributing to their aortic accumulation and aneurysm progressionIuliia O. PeshkovaTuran AghayevAliia R. FatkhullinaPetr MakhovElizaveta K. TiterinaSatoru EguchiYin Fei TanAndrew V. KossenkovMarina V. KhorevaLyudmila V. GankovskayaStephen M. SykesEkaterina K. KoltsovaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Iuliia O. Peshkova Turan Aghayev Aliia R. Fatkhullina Petr Makhov Elizaveta K. Titerina Satoru Eguchi Yin Fei Tan Andrew V. Kossenkov Marina V. Khoreva Lyudmila V. Gankovskaya Stephen M. Sykes Ekaterina K. Koltsova IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development
description	Immune cells contribute to the aortic wall destruction during abdominal aortic aneurysm (AAA) development. Here, Peshkova et al. show that cytokine signaling through interleukin-27 receptor is required for Angiotensin II-induced myelopoiesis and mature myeloid cells production, thus contributing to their aortic accumulation and aneurysm progression
format	article
author	Iuliia O. Peshkova Turan Aghayev Aliia R. Fatkhullina Petr Makhov Elizaveta K. Titerina Satoru Eguchi Yin Fei Tan Andrew V. Kossenkov Marina V. Khoreva Lyudmila V. Gankovskaya Stephen M. Sykes Ekaterina K. Koltsova
author_facet	Iuliia O. Peshkova Turan Aghayev Aliia R. Fatkhullina Petr Makhov Elizaveta K. Titerina Satoru Eguchi Yin Fei Tan Andrew V. Kossenkov Marina V. Khoreva Lyudmila V. Gankovskaya Stephen M. Sykes Ekaterina K. Koltsova
author_sort	Iuliia O. Peshkova
title	IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development
title_short	IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development
title_full	IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development
title_fullStr	IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development
title_full_unstemmed	IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development
title_sort	il-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b6343cfed5b940ac92570f7ff3c8787a
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IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development

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