IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development

IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development

Immune cells contribute to the aortic wall destruction during abdominal aortic aneurysm (AAA) development. Here, Peshkova et al. show that cytokine signaling through interleukin-27 receptor is required for Angiotensin II-induced myelopoiesis and mature myeloid cells production, thus contributing to...

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Main Authors: Iuliia O. Peshkova, Turan Aghayev, Aliia R. Fatkhullina, Petr Makhov, Elizaveta K. Titerina, Satoru Eguchi, Yin Fei Tan, Andrew V. Kossenkov, Marina V. Khoreva, Lyudmila V. Gankovskaya, Stephen M. Sykes, Ekaterina K. Koltsova
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/b6343cfed5b940ac92570f7ff3c8787a
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https://doaj.org/article/b6343cfed5b940ac92570f7ff3c8787a

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