IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development

IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development

Immune cells contribute to the aortic wall destruction during abdominal aortic aneurysm (AAA) development. Here, Peshkova et al. show that cytokine signaling through interleukin-27 receptor is required for Angiotensin II-induced myelopoiesis and mature myeloid cells production, thus contributing to...

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Autores principales: Iuliia O. Peshkova, Turan Aghayev, Aliia R. Fatkhullina, Petr Makhov, Elizaveta K. Titerina, Satoru Eguchi, Yin Fei Tan, Andrew V. Kossenkov, Marina V. Khoreva, Lyudmila V. Gankovskaya, Stephen M. Sykes, Ekaterina K. Koltsova
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/b6343cfed5b940ac92570f7ff3c8787a
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