Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy
Abstract Spinocerebellar ataxia type 2 (SCA2) is an incurable and genetic neurodegenerative disorder. The disease is characterized by progressive degeneration of several brain regions, resulting in severe motor and non-motor clinical manifestations. The mutation causing SCA2 disease is an abnormal e...
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Autores principales: | Adriana Marcelo, Inês T. Afonso, Ricardo Afonso-Reis, David V. C. Brito, Rafael G. Costa, Ana Rosa, João Alves-Cruzeiro, Benedita Ferreira, Carina Henriques, Rui J. Nobre, Carlos A. Matos, Luís Pereira de Almeida, Clévio Nóbrega |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/b63aca6d2a754206b576ac751ce40616 |
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