Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy

Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy

Abstract Spinocerebellar ataxia type 2 (SCA2) is an incurable and genetic neurodegenerative disorder. The disease is characterized by progressive degeneration of several brain regions, resulting in severe motor and non-motor clinical manifestations. The mutation causing SCA2 disease is an abnormal e...

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Main Authors: Adriana Marcelo, Inês T. Afonso, Ricardo Afonso-Reis, David V. C. Brito, Rafael G. Costa, Ana Rosa, João Alves-Cruzeiro, Benedita Ferreira, Carina Henriques, Rui J. Nobre, Carlos A. Matos, Luís Pereira de Almeida, Clévio Nóbrega
Format: article
Language:EN
Published: Nature Publishing Group 2021
Subjects:
Cytology
QH573-671
Online Access:https://doaj.org/article/b63aca6d2a754206b576ac751ce40616
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https://doaj.org/article/b63aca6d2a754206b576ac751ce40616

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