Protochlamydia induces apoptosis of human HEp-2 cells through mitochondrial dysfunction mediated by chlamydial protease-like activity factor.

Protochlamydia induces apoptosis of human HEp-2 cells through mitochondrial dysfunction mediated by chlamydial protease-like activity factor.

Obligate amoebal endosymbiotic bacterium Protochlamydia with ancestral pathogenic chlamydial features evolved to survive within protist hosts, such as Acanthamoba, 0.7-1.4 billion years ago, but not within vertebrates including humans. This observation raises the possibility that interactions betwee...

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Autores principales: Junji Matsuo, Shinji Nakamura, Atsushi Ito, Tomohiro Yamazaki, Kasumi Ishida, Yasuhiro Hayashi, Mitsutaka Yoshida, Kaori Takahashi, Tsuyoshi Sekizuka, Fumihiko Takeuchi, Makoto Kuroda, Hiroki Nagai, Kyoko Hayashida, Chihiro Sugimoto, Hiroyuki Yamaguchi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b63ded3e522541ceaac565806ee32dd9
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