Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.

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Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.

Viruses have evolved means to manipulate the host's ubiquitin-proteasome system, in order to down-regulate antiviral host factors. The Vpx/Vpr family of lentiviral accessory proteins usurp the substrate receptor DCAF1 of host Cullin4-RING ligases (CRL4), a family of modular ubiquitin ligases in...

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Détails bibliographiques
Auteurs principaux:	Sofia Banchenko, Ferdinand Krupp, Christine Gotthold, Jörg Bürger, Andrea Graziadei, Francis J O'Reilly, Ludwig Sinn, Olga Ruda, Juri Rappsilber, Christian M T Spahn, Thorsten Mielke, Ian A Taylor, David Schwefel
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2021
Sujets:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/b63e6e33cdeb4efb8f380f91c2f56491
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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