Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography

Sachi Kojima, Toshihiro Inoue, Takahiro Kawaji, Hidenobu TaniharaDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Kumamoto, JapanPurpose: To determine the clinical features of tear fluid signs associated with filtration blebs via three-dimensional anterior segmen...

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Autores principales:	Kojima S, Inoue T, Kawaji T, Tanihara H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b63e7cf75cf344e7984dda59c15a886d
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spelling	oai:doaj.org-article:b63e7cf75cf344e7984dda59c15a886d2021-12-02T02:46:50ZTear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography1177-5483https://doaj.org/article/b63e7cf75cf344e7984dda59c15a886d2014-04-01T00:00:00Zhttp://www.dovepress.com/tear-fluid-signs-associated-with-filtration-blebs-as-demonstrated-by-t-a16500https://doaj.org/toc/1177-5483 Sachi Kojima, Toshihiro Inoue, Takahiro Kawaji, Hidenobu TaniharaDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Kumamoto, JapanPurpose: To determine the clinical features of tear fluid signs associated with filtration blebs via three-dimensional anterior segment optical coherence tomography (3D AS-OCT).Methods: In total, 152 eyes (130 patients) with glaucoma that underwent trabeculectomy with mitomycin C were evaluated retrospectively. We investigated tear fluid signs associated with filtration blebs, using 3D AS-OCT with custom software, and compared the findings of lower tear meniscus. We also analyzed postoperative intraocular pressure and the bleb parameters of filtration blebs between eyes with and without tear fluid signs.Results: We found tear fluid signs associated with filtration blebs in 45 (30%) of 152 eyes. The mean postoperative intraocular pressure of the eyes with the tear fluid sign in a filtration bleb was significantly lower than that in eyes without the tear fluid sign (P<0.001). Blebs with tear fluid signs have more frequent identifiable filtration openings, greater total height, increased fluid-filled cavity height, and less wall intensity compared with blebs without these signs.Conclusion: We identified tear fluid signs in AS-OCT images on or along filtration blebs that depended on bleb morphology. The occurrence of these signs may be related to the presence of functional blebs, which may thereby control postoperative intraocular pressure.Keywords: filtration bleb, trabeculectomy, 3D AS-OCT, tear fluid signKojima SInoue TKawaji TTanihara HDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 767-772 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kojima S Inoue T Kawaji T Tanihara H Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
description	Sachi Kojima, Toshihiro Inoue, Takahiro Kawaji, Hidenobu TaniharaDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Kumamoto, JapanPurpose: To determine the clinical features of tear fluid signs associated with filtration blebs via three-dimensional anterior segment optical coherence tomography (3D AS-OCT).Methods: In total, 152 eyes (130 patients) with glaucoma that underwent trabeculectomy with mitomycin C were evaluated retrospectively. We investigated tear fluid signs associated with filtration blebs, using 3D AS-OCT with custom software, and compared the findings of lower tear meniscus. We also analyzed postoperative intraocular pressure and the bleb parameters of filtration blebs between eyes with and without tear fluid signs.Results: We found tear fluid signs associated with filtration blebs in 45 (30%) of 152 eyes. The mean postoperative intraocular pressure of the eyes with the tear fluid sign in a filtration bleb was significantly lower than that in eyes without the tear fluid sign (P<0.001). Blebs with tear fluid signs have more frequent identifiable filtration openings, greater total height, increased fluid-filled cavity height, and less wall intensity compared with blebs without these signs.Conclusion: We identified tear fluid signs in AS-OCT images on or along filtration blebs that depended on bleb morphology. The occurrence of these signs may be related to the presence of functional blebs, which may thereby control postoperative intraocular pressure.Keywords: filtration bleb, trabeculectomy, 3D AS-OCT, tear fluid sign
format	article
author	Kojima S Inoue T Kawaji T Tanihara H
author_facet	Kojima S Inoue T Kawaji T Tanihara H
author_sort	Kojima S
title	Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
title_short	Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
title_full	Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
title_fullStr	Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
title_full_unstemmed	Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
title_sort	tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/b63e7cf75cf344e7984dda59c15a886d
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Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography

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